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Integrase Inhibitors

for Veterans and the Public

Integrase Inhibitors

This class of anti-HIV drugs works by blocking an enzyme (HIV integrase) that the virus needs in order to splice copies of itself into human DNA.

  • Bictegravir
  • Dolutegravir (brand name: Tivicay®)
  • Elvitegravir (brand name: Vitekta®) (Note: Elvitegravir must be "boosted" with a pharmacokinetic enhancer, either cobicistat or ritonavir.)
  • Raltegravir (brand name: Isentress®)

Some integrase inhibitors are combined with NRTIs in fixed-dose combination tablets. (See multi-class drug combinations.)