for Veterans and the Public
This class of anti-HIV drugs works by blocking an enzyme (HIV integrase) that the virus needs in order to splice copies of itself into human DNA.
- Dolutegravir (brand name: Tivicay®)
- Elvitegravir (brand name: Vitekta®) (Note: Elvitegravir must be "boosted" with a pharmacokinetic enhancer, either cobicistat or ritonavir.)
- Raltegravir (brand name: Isentress®)
Some integrase inhibitors are combined with NRTIs in fixed-dose combination tablets. (See multi-class drug combinations.)