for Veterans and the Public
Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs or non-nukes)
The second type of antiretroviral drugs is the non-nucleoside reverse transcriptase inhibitors (NNRTIs). These drugs are sometimes called non-nucleosides or "non-nukes."
These drugs also prevent HIV from using reverse transcriptase to make copies of itself, but in a different way.
These NNRTIs are available:
- Edurant® (rilpivirine)
- Intelence® (etravirine)
- Rescriptor® (delavirdine)
- Sustiva® (efavirenz)
- Viramune® (nevirapine)
Some NNRTIs are combined with NRTIs in fixed-dose combination tablets. (See multi-class drug combinations)