HIV/AIDS: For Patients and the Public
 | | |
| AZT
(Retrovir, zidovudine, ZDV)
- Type of Drug: Nucleoside Reverse Transcriptase Inhibitor
Nucleoside reverse transcriptase inhibitors were the first type of drug available to treat HIV. They are also known as NRTIs, nucleoside analogues, or "nukes."
When the HIV virus enters a healthy cell, it attempts to make copies of itself. It does this by using an enzyme called reverse transcriptase. NRTIs block that enzyme, so HIV cannot make new copies of itself.
Notes on taking this medication- No food restrictions, can take with or without food
- Persons with kidney problems may need an adjustment of their dose of AZT
- Cannot take AZT with Zerit
Side effects- Nausea; stomach discomfort; headache
- Symptoms of anemia (low red blood cell count): fatigue; shortness of breath
- More rarely: muscle wasting; neutropenia (low white blood cell count)
- Changes in body-fat distribution
See accompanying chart: Tips for Common Side Effects My doctor's instructionsDisclaimer:This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist. | | | |
| | * Indicates a link that will take you outside the Department of Veterans Affairs website.
** Indicates a non-U.S. government website; VA does not endorse and is not responsible for the content of the linked site. |
|
Reviewed/Updated Date: December 15, 2009
