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GERD Dosage Recommendations: ATV with PPIs or H2RAs

for Health Care Providers

Dosage Recommendations: ATV with PPIs or H2RAs

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ARV-Naive PatientsARV-Experienced Patients
Source: Reyataz package label
PPI
  • ATV/r 300/100 mg QD; PPI dosage not to exceed the equivalent of omeprazole 20 mg QD, with the PPI to be taken approximately 12 hours before ATV/r.
  • Unboosted ATV is not recommended.
  • PPIs are not recommended.
H2RA
  • ATV/r 300/100 mg QD; H2RA dosage not to exceed the equivalent of famotidine 40 mg BID; give ATV/r with the H2RA and/or ≥10 hours after the H2RA.
  • Unboosted ATV is not recommended; if used with H2RA, H2RA should not exceed the equivalent of famotidine 20 mg per dose or daily total of 40 mg; give ≥2 hours after and/or ≥10 hours before ATV/r.
  • ATV/r 300/100 mg QD; H2RA dosage not to exceed the equivalent of famotidine 20 mg BID; give ATV/r with the H2RA and/or ≥10 hours after the H2RA.
  • If TDF is used in the regimen, give ATV/r 400/100 mg QD. Administer H2RA as described above.
  • Unboosted ATV is not recommended.

From Gastroesophageal Reflux Disease
Primary Care of Veterans with HIV
Office of Clinical Public Health Programs
Veterans Health Administration, 2009