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Drug Dosing Toolkit: Reyataz

for Veterans and the Public

Reyataz (atazanavir)

Type of Drug: Protease Inhibitor
Once HIV has infected a cell and made copies of itself, it uses an enzyme called protease to process itself correctly so it can be released from the cell to infect other cells. Protease inhibitors work by blocking that enzyme.

Approved adult dosing

two 200 mg capsules Reyataz once a day

  • Daily
    Reyataz 200Reyataz 200

    Reyataz 200 mg

Note: This dose may not be appropriate for people who have taken other HIV medications, or who are currently taking Viread or Truvada

one 300 mg capsule Reyataz + one 100 mg tablet or capsule Norvir, once a day

  • Daily
    Reyataz 300

    Reyataz 300 mg

    Norvir tablet


two 150 mg capsules Reyataz + one 100 mg tablet or capsule Norvir, once a day

  • Daily
    Reyataz 150Reyataz 150

    Reyataz 150 mg

    Norvir tablet


Notes on taking this medication

  • Always take with food, to increase absorption
  • Reyataz interacts with many other drugs; persons using Reyataz with those drugs may need an adjustment to their dose of Reyataz or the other drugs; consult your medical provider
  • Reyataz interacts with medicines for indigestion, heartburn, and ulcers, including medicines available over the counter; check with your medical provider before using these medicines

Side effects

  • Jaundice (yellow eyes and/or yellow skin), especially when used with Norvir; this is rarely serious, but let your medical provider know if this develops
  • Abdominal pain; liver inflammation and increased liver enzyme levels
  • Uncommon: elevations in cholesterol and triglycerides

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.