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Lymphomas associated with HIV include a large group of cancers that begin in the cells of the immune system. The cancers can spread to different parts of the body, such as the central nervous system, liver, bone marrow, and gastrointestinal tract. Symptoms depend on where the cancer resides.

Treatment varies depending on the specific cancer, but can include radiation and chemotherapy. HIV drugs, by boosting the immune system, can help the body fight the cancer, too. In fact, the development of effective combination HIV therapy has greatly improved the outlook for persons with HIV-associated lymphoma.