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Drug Dosing Toolkit: Complera

for Veterans and the Public

Complera (Edurant + Viread + Emtriva)

Type of Drug: Fixed-Dose Combination
Fixed-dose combinations combine the most commonly prescribed doses of 2 or more medications into a single pill.

Bring a printout of this page to discuss with your doctor during your next visit. List your questions at the bottom of the page.

Approved adult dosing

Edurant 25 mg + Viread 300 mg + Emtriva 200 mg in a single tablet

one tablet Complera

  • Daily
    Complera

    Complera

Notes on taking this medication

  • Take with a full meal (do not take without food)
  • Medicines for indigestion, heartburn, and ulcers (including medicines available over the counter) may block the body's absorption of Edurant; check with your medical provider before using these medicines
  • Edurant can interact with other drugs; consult your medical provider
  • Persons with kidney problems may need an adjustment to their doses of the component drugs, so may not be able to take this combination pill

Same side effects as

Edurant

  • Depression, mood changes
  • Nausea
  • Rash

Viread

  • Gassiness; abdominal discomfort; nausea; diarrhea
  • Kidney impairment
  • Bone impairment
  • Viread is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B

Emtriva

  • Skin discoloration (particularly in dark-skinned people)
  • Emtriva is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B

See accompanying chart: Tips for Common Side Effects

Notes

Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.