for Veterans and the Public
AZT + lamivudine (Combivir)
- Type of Drug: Fixed-Dose Combination
- Fixed-dose combinations include several medications in 1 pill.
Bring a printout of this page to discuss with your doctor during your next visit. List your questions at the bottom of the page.
Approved adult dosing
AZT 300 mg + lamivudine (3TC, Epivir) 150 mg in a single tablet
one tablet Combivir two times a day
Note: Generic formulations are available; these generic pills may have different shapes and colors than the one shown above.
Notes on taking this medication
- Because of the possibility of serious side effects from AZT, this combination is not generally recommended for treatment of HIV; if you are taking AZT + lamivudine (eg, Combivir), talk with your clinician about changing to a different medication
- No food restrictions, can take with or without food
- Persons with kidney problems may need an adjustment to their doses of the component drugs, so may not be able to take this combination pill
Same possible side effects as
- Nausea; stomach discomfort; headache
- Symptoms of anemia (low red blood cell count): fatigue; shortness of breath
- More rarely: muscle wasting; neutropenia (low white blood cell count)
- Changes in body-fat distribution
Lamivudine (3TC, Epivir)
- Side effects are rare but include headaches and general sense of feeling ill
- Lamivudine is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B
See accompanying chart: Tips for Common Side Effects
Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.