for Veterans and the Public
CD4 counts and infections
The weaker your immune system, the more likely you are to get an OI.
In general, here's how a CD4 count relates to your risk of OIs:
Above 500 CD4 cells
If you are taking your HIV medications regularly, no unusual infections are likely to occur.
200-500 CD4 cells
There is an increased risk for certain conditions, such as shingles, thrush, skin infections, bacterial sinus and lung infections, and TB.
<200 CD4 cells
There is an increased risk for PCP (pneumonia) and other infections, and you should begin treatment to prevent them.
<100 CD4 cells
If counts are below 100, preventive treatment should begin for Mycobacterium avium complex (MAC),a life-threatening bacterial infection and toxoplasmosis, a disease that results from infection with the Toxoplasma gondii parasite (if not already on PCP prophylaxis that helps prevent toxoplasmosis, like trimethoprim/sulfamethoxazole).
<50 CD4 cells
There is an increased risk for cytomegalovirus (a common infection and member of the herpesvirus family).