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FAQ: Is there a once-a-day pill for HIV?

for Veterans and the Public

Frequently Asked Questions

Q: Is there a once-a-day pill for HIV?

Yes. There currently there are three combination pills that include an entire regimen in a single pill. The three once-a-day pills, with their components, are:

  • Atripla
    • 600 mg of efavirenz (Sustiva)
    • 300 mg of tenofovir (Viread)
    • 200 mg of emtricitabine (Emtriva)
  • Complera
    • 25 mg of rilpivirine (Edurant)
    • 300 mg of tenofovir (Viread)
    • 200 mg of emtricitabine (Emtriva)
  • Stribild
    • 150 mg of elvitegravir
    • 150 mg of cobicistat
    • 300 mg of tenofovir (Viread)
    • 200 mg of emtricitabine (Emtriva)

People who might benefit from these single-pill combinations include:

  • Those starting antiretroviral therapy for the first time
  • Those who would like to simplify their regimen from the same or similar individual component medications (for example, Sustiva + Truvada)
  • Those who would like to switch from a more complicated regimen and have not developed resistance to any of the drugs that these single-pill regimens contain

In the next year or two, it is hoped that other one-pill, once-daily regimens will become available.