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Chronic Hepatitis C Virus (HCV) Infection: Treatment Considerations

for Veterans and the Public

Chronic Hepatitis C Virus (HCV) Infection: Treatment Considerations


Full PDF Version


This revision (October 18, 2017) incorporates updates to treatment regimens for chronic hepatitis C virus (HCV) infection, genotypes 1-4, including re-treatment of patients who previously failed direct-acting antiviral therapy. New and updated sections include:

The Panel continues to recommend:

  • HIV/HCV-coinfected patientsPDF icon receive the same HCV antiviral regimens as HCV-monoinfected patients unless ledipasvir/sofosbuvir is being considered, in which case a 12-week regimen should be used (instead of an 8-week regimen).
  • HBV testing and monitoring prior to starting HCV DAA. Details can be found in Appendix DPDF icon.