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HIV/AIDS

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FAQ: Is there a once-a-day pill for HIV?

for Veterans and the Public

Frequently Asked Questions

Q: Are there once-a-day pills for HIV?

Yes. There currently there are 7 combination pills that include an entire regimen in a single pill. The 7 once-a-day pills, with their components, are:

  • Atripla
    • efavirenz (Sustiva) 600 mg
    • tenofovir DF (Viread) 300 mg
    • emtricitabine (Emtriva) 200 mg
  • Biktarvy
    • bictegravir 50 mg
    • tenofovir alafenamide 25 mg
    • emtricitabine (Emtriva) 200 mg
  • Complera
    • rilpivirine (Edurant) 25 mg
    • tenofovir DF (Viread) 300 mg
    • emtricitabine (Emtriva) 200 mg
  • Odefsey
    • rilpivirine (Edurant) 25 mg
    • tenofovir alafenamide 25 mg
    • emtricitabine (Emtriva) 200 mg
  • Stribild
    • elvitegravir (Vitekta) 150 mg
    • cobicistat (Tybost) 150 mg
    • tenofovir DF (Viread) 300 mg
    • emtricitabine (Emtriva) 200 mg
  • Genvoya
    • elvitegravir (Vitekta) 150 mg
    • cobicistat (Tybost) 150 mg
    • tenofovir alafenamide 25 mg
    • emtricitabine (Emtriva) 200 mg
  • Triumeq
    • dolutegravir (Tivicay) 50 mg
    • abacavir (Ziagen) 600 mg
    • lamivudine (Epivir) 300 mg

People who might benefit from these single-pill combinations include:

  • Those starting antiretroviral therapy for the first time
  • Those who would like to simplify their regimen from the same or similar individual component medications (for example, Tivicay + Epzicom)
  • Those who would like to switch from a more complicated regimen and have not developed resistance to any of the drugs that these single-pill regimens contain

Other one-pill, once-daily regimens are expected to become available in the future.