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FAQ: Can I take hep C medications along with my HIV medications?

for Veterans and the Public

Frequently Asked Questions

Q: I have hepatitis C and hope to start treatment soon. Can I take hep C medications along with my HIV medications?

It's great that you are about to start hepatitis C treatment--good luck with it.

Yes, you can and should continue HIV medications while you take medications for hepatitis C, if at all possible. But, some HIV medications interact with some of the hepatitis C medicines (the so-called direct acting antivirals, or DAAs). This could cause unwanted increases or decreases of drug levels in your body (depending on the specific interaction) and thus increase the risk of side effects (if a drug level rises) or of treatment failure (if a drug level drops).

So, it is very important for your clinicians to be sure that the two sets of medications are compatible. In some cases, it may be necessary to change the HIV regimen in order to allow treatment with certain DAAs. Please discuss this with your HIV and hepatitis clinicians before you start hepatitis C treatment.