for Veterans and the Public
tenofovir disoproxyl fumarate, TDF (Viread)
- Type of Drug: Nucleotide Reverse Transcriptase Inhibitor
Nucleotide reverse transcriptase inhibitors are also known as NRTIs, nucleotide analogues, or "nukes."
When the HIV virus enters a healthy cell, it attempts to make copies of itself. It does this by using an enzyme called reverse transcriptase. NRTIs block that enzyme, so HIV cannot make new copies of itself.
Bring a printout of this page to discuss with your doctor during your next visit. List your questions at the bottom of the page.
Approved adult dosing
one 300 mg tablet Viread once a day
Notes on taking this medication
- No food restrictions, can take with or without food
- Persons with kidney problems may need an adjustment to their dosing schedule, or may need a different drug
Possible side effects
- Gassiness; abdominal discomfort; nausea; diarrhea
- Kidney impairment
- Bone impairment
- Viread is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B
See accompanying chart: Tips for Common Side Effects
Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.