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Drug Dosing Toolkit: Isentress (Raltegravir)

for Veterans and the Public

Isentress (raltegravir)

Type of Drug: Integrase Inhibitor
Integrase inhibitors work by blocking an enzyme (HIV integrase) that the virus needs in order to make more virus.

Bring a printout of this page to discuss with your doctor during your next visit. List your questions at the bottom of the page.

Approved adult dosing

one 400 mg tablet Isentress two times a day

  • Morning
    Isentress

    Isentress

  • Evening
    Isentress

    Isentress

Two 600 mg tablet Isentress HD once a day

  • Daily
    Isentress HDIsentress HD

    Isentress HD 600 mg

Notes on taking this medication

  • Isentress interacts with certain antacids and laxatives, and with calcium and iron supplements; check with your medical provider before using these.
  • Isentress interacts with certain tuberculosis medications. If you're being treated for TB or MAC, let your HIV provider know.

Side effects

  • Usually well tolerated; may cause nausea; diarrhea; headache; muscle aches; rash
  • Contact your doctor promptly if you experience unexplained muscle pain, tenderness, or weakness

See accompanying chart: Tips for Common Side Effects

Notes

Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.