HIV/AIDS: For Patients and the Public
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| Zerit
(stavudine, d4T)
- Type of Drug: Nucleoside Reverse Transcriptase Inhibitor
Nucleoside reverse transcriptase inhibitors were the first type of drug available to treat HIV. They are also known as NRTIs, nucleoside analogues, or "nukes."
When the HIV virus enters a healthy cell, it attempts to make copies of itself. It does this by using an enzyme called reverse transcriptase. NRTIs block that enzyme, so HIV cannot make new copies of itself.
Notes on taking this medication- No food restrictions, can take with or without food
- Persons with kidney problems may need to adjust the doses of Zerit
- Do not take Zerit with AZT (Retrovir), Combivir, Trizivir, or Videx EC
Side effects- Pain or tingling in feet or hands (peripheral neuropathy)
- Nausea; vomiting; abdominal pain; headache; rash
- Pancreatitis
- Changes in body fat distribution, especially fat loss; may be severe
- Abnormalities in cholesterol levels
- Rare but serious: increase of lactic acid in the blood
See accompanying chart: Tips for Common Side Effects My doctor's instructionsDisclaimer:This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist. | | | |
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Reviewed/Updated Date: December 15, 2009
