Once HIV has infected a cell and made copies of itself, it uses an enzyme called protease to process itself correctly so it can be released from the cell to infect other cells. Protease inhibitors work by blocking that enzyme.
Approved adult dosing
For those who have taken antiretroviral drugs before: one 600 mg tablet Prezista + one 100 mg capsule Norvir, two times a day
Morning
Prezista 600 mg
+
Norvir
Evening
Prezista 600 mg
+
Norvir
For those who have NEVER taken antiretroviral drugs: two 400 mg tablets Prezista + one 100 mg capsule Norvir, once a day
Daily
Prezista 400 mg each
+
Norvir
Note: Prezista has been available as a 300 mg tablet (dose is two 300 mg tablets + one 100 mg capsule Norvir, two times a day), but this is being phased out.
Notes on taking this medication
Must take Prezista with Norvir; it is approved only with the use of Norvir
Must take with food
Prezista interacts with many other drugs; persons using Prezista with those drugs may need an adjustment to their dose of Prezista or the other drugs; consult your medical provider
Side effects
Nausea; diarrhea; stomach discomfort
Rash
Liver inflammation and increased liver enzyme levels
Elevations in cholesterol and triglycerides
Elevated blood sugar
Abnormal accumulation of body fat
Persons who are allergic to sulfa drugs may be allergic to Prezista
This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.
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