for Health Care Providers
Virologic Features of Liver Disease
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| HBV Diagnostic Tests and Interpretation | ||||||
|---|---|---|---|---|---|---|
| Acute Hepatitis B | Recovery from Acute Hepatitis B | Chronic HBeAg+ Disease | Chronic HBeAg- Disease | Successful Vaccination | Recovery from Acute Hepatitis B with Loss of HBsAb | |
| HBsAg | + (may clear) | - | + | + | - | - |
| Anti-HBs | - | + | - | - | + | - |
| Anti-HBc IgM | + (may be only marker during window period) | - | - | - | - | - |
| Anti-HBc | + | + | + | + | - | + (also termed "isolated HBcAb+") |
| HBeAg | + | - | + | - | - | - |
| Anti-HBe | - | + (in some cases) | - | + | - | + (in some cases) |
| DNA (PCR if required) | + | - | + | + | - | - |
| HCV Diagnostic Tests and Interpretation | ||||||
| Acute Hepatitis C | Spontaneously Resolved or Successfully Treated Hepatitis C | Chronic Hepatitis C | Low-Level Chronic Hepatitis C | False-Positive Hepatitis C | ||
| Anti-HCV | - or + | + | + | + | + | |
| HCV RIBA | - or + | + | + | + | - | |
| HCV RNA Quantitative | + | - | + | - | - | |
| HCV RNA Qualitative | + (may be only marker during window period) | - | + | + | - | |
| HCV Genotype | + | - | + | + or - | - | |
From Liver Disease and Cirrhosis
Primary Care of Veterans with HIV
Office of Clinical Public Health Programs
Veterans Health Administration, 2009
