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HIV/AIDS Histopathologic/Microscopic Images

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Histopathologic/Microscopic Studies

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Lymphocytic interstitial pneumonitis/pulmonary lymphocytic hyperplasia: lung biopsy

image of Lymphocytic interstitial pneumonitis/pulmonary lymphocytic hyperplasia: lung biopsy

Credits

Dr. Claire Langston, Baylor College of Medicine, Houston, Texas. Pediatric AIDS Pictoral Atlas, Baylor International Pediatric AIDS Initiative

Description

Lung biopsy specimen showing mononuclear interstitial infiltration in a child with HIV infection and lymphocytic interstitial pneumonitis/pulmonary lymphocytic hyperplasia (LIP/PLH). The pathogenesis of LIP/PLH is poorly understood, but Epstein-Barr virus has been implicated as a cofactor in its development.