for Health Care Providers
New ARV Interactions, April-July 2009
Back to Updates to the Database of ARV Drug Interactions
| Drug One | Drug Two | Clinical Effects | Mechanisms | Management |
|---|---|---|---|---|
Source: McNicholl I. HIV InSite Database of Antiretroviral Drug Interactions . University of California San Francisco: Center for HIV Information; 2009 | ||||
| Tenofovir | Etravirine | No dosage adjustment necessary | ||
| Nevirapine | Fluconazole | Possibly ↑ nevirapine effects | Inhibition of CYP450 3A4 by fluconazole | No dosage adjustment necessary |
| Atazanavir | Simvastatin | ↑ simvastatin effects (eg, myopathy, rhabdomyolysis) | Inhibition of CYP450 3A4 by atazanavir | Do not coadminister Alternative agents: Atorvastatin (low dose); pravastatin |
From New ARV Interactions, April-July 2009
HIV Meds Quarterly Research Brief
Summer 2009
