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Non-nucleoside reverse transcriptase inhibitors (NNRTIs or 'non-nukes')

for Veterans and the Public

Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs or non-nukes)

The second type of antiretroviral drugs is the non-nucleoside reverse transcriptase inhibitors (NNRTIs). These drugs are sometimes called non-nucleosides or "non-nukes."

These drugs also prevent HIV from using reverse transcriptase to make copies of itself, but in a different way.

These NNRTIs are available:

  • Edurant® (rilpivirine)
  • Intelence® (etravirine)
  • Rescriptor® (delavirdine)
  • Sustiva® (efavirenz)
  • Viramune® (nevirapine)