for Veterans and the Public
Selzentry (maraviroc)
- Type of Drug: Chemokine Coreceptor Antagonist
To infect a cell, HIV must bind to two types of molecules on the cell's surface.
One of these is called a chemokine coreceptor. Drugs known as chemokine coreceptor antagonists block the virus from binding to the molecules.
Note: Because the drug level of Selzentry in your body is affected by many medications, the recommended dosage of Selzentry depends on what other medications you are taking. It is important to discuss this with your medical provider before you start taking Selzentry or any other medication.
Approved adult dosing
one 300 mg tablet, two times a day (standard dosage)
Morning
Selzentry 300 mg
Evening
Selzentry 300 mg
Note: Other HIV medications compatible with this dosage: Aptivus, AZT, Emtriva, Epivir, Fuzeon, Videx-EC, Viramune, Viread, Zerit, Ziagen; consult your medical provider
one 150 mg tablet, two times a day
Morning
Selzentry 150 mg
Evening
Selzentry 150 mg
Note: This dose recommended if Selzentry is used in a regimen that contains Crixivan, Invirase, Lexiva, Norvir, Prezista, Reyataz, Viracept, or Rescriptor; consult your medical provider
two 300 mg tablets, two times a day
Morning
Selzentry 300 mg
Evening
Selzentry 300 mg
Note: This dose recommended if Selzentry is used in a regimen that contains Sustiva or Intellence without Crixivan, Invirase, Lexiva, Norvir, Prezista, Reyataz, or Viracept; consult your medical provider
Notes on taking this medication
- Many medications used to treat HIV-related illnesses and other conditions interact with Selzentry. Persons using Selzentry with these medications may need an adjustment to their dosage of Selzentry; consult your medical provider
- Selzentry only works against HIV that binds to a molecule called CCR5 (this type of HIV is sometimes referred to as "R5 virus"). Before you start taking Selzentry, you must have a special blood test (called a tropism assay) to determine whether you have R5 virus or another type of HIV
Side effects
- Cough; upper respiratory tract infections
- Muscle and joint pain
- Liver inflammation; rash; allergic reaction
- Diarrhea
- Sleep disturbance
See accompanying chart: Tips for Common Side Effects
My doctor's instructions
Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.
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