HIV/AIDS

Quick Links

Veterans Crisis Line Badge
My healthevet badge

Drug Dosing Toolkit: Kaletra

for Veterans and the Public

Kaletra (lopinavir/ritonavir)

Type of Drug: Protease Inhibitor
Once HIV has infected a cell and made copies of itself, it uses an enzyme called protease to process itself correctly so it can be released from the cell to infect other cells. Protease inhibitors work by blocking that enzyme.

Approved adult dosing

Lopinavir 200 mg + ritonavir 50 mg in a single tablet

two tablets Kaletra two times a day

  • Morning
    Kaletra (lopinavir/ritonavir)Kaletra (lopinavir/ritonavir)

    Kaletra

  • Evening
    Kaletra (lopinavir/ritonavir)Kaletra (lopinavir/ritonavir)

    Kaletra

Lopinavir 200 mg + ritonavir 50 mg in a single tablet

four tablets Kaletra once a day

  • Daily
    Kaletra (lopinavir/ritonavir)Kaletra (lopinavir/ritonavir)Kaletra (lopinavir/ritonavir)Kaletra (lopinavir/ritonavir)

    Kaletra

Note: This once-daily dosage may not be appropriate for people who have taken other HIV medications in the past; consult your medical provider

Notes on taking this medication

  • Take with or without food
  • Kaletra interacts with many other drugs; persons using Kaletra with those drugs may need an adjustment to their dose of Kaletra or the other drugs; consult your medical provider

Side effects

  • Nausea; vomiting; diarrhea; headaches
  • Liver inflammation and increased liver enzyme levels
  • Elevations in cholesterol and triglycerides
  • Abnormal accumulation of body fat
  • Increased blood sugar

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.