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HIV/AIDS

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Drug Dosing Toolkit: Invirase

for Veterans and the Public

Invirase (saquinavir)

Type of Drug: Protease Inhibitor
Once HIV has infected a cell and made copies of itself, it uses an enzyme called protease to process itself correctly so it can be released from the cell to infect other cells. Protease inhibitors work by blocking that enzyme.

Approved adult dosing

two 500 mg tablets Invirase + one 100 mg tablet or capsule Norvir, two times a day

  • Morning
    Invirase 500Invirase 500

    Invirase 500 mg

    +
    Norvir 100

    Norvir

  • Evening
    Invirase 500Invirase 500

    Invirase 500 mg

    +
    Norvir 100

    Norvir

five 200 mg capsules Invirase + one 100 mg tablet or capsule Norvir, two times a day

  • Morning
    Invirase 200Invirase 200Invirase 200Invirase 200Invirase 200

    Invirase 200 mg

    +
    Norvir 100

    Norvir

  • Evening
    Invirase 200Invirase 200Invirase 200Invirase 200Invirase 200

    Invirase 200 mg

    +
    Norvir 100

    Norvir

Notes on taking this medication

  • Take with food or after a meal
  • Invirase interacts with many other drugs; persons using Invirase with those drugs may need an adjustment to their dose of Invirase or the other drugs; consult your medical provider

Side effects

  • Nausea; vomiting; diarrhea; stomach discomfort; headache
  • Liver inflammation and increased liver enzyme levels
  • Elevations in cholesterol and triglycerides
  • Abnormal accumulation of body fat

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.