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Drug Dosing Toolkit: Complera

for Veterans and the Public

Complera (Edurant + Viread + Emtriva)

Type of Drug: Fixed-Dose Combination
Fixed-dose combinations combine the most commonly prescribed doses of several medications into 1 pill.

Approved adult dosing

Edurant 25 mg + Viread 300 mg + Emtriva 200 mg in a single tablet

one tablet Complera

  • Daily
    Complera

    Complera

Notes on taking this medication

  • Take with a full meal (do not take without food)
  • Edurant interacts with medicines for indigestion, heartburn, and ulcers, including medicines available over the counter; check with your medical provider before using these medicines
  • Edurant can interact with other drugs; consult your medical provider
  • Persons with kidney problems may need an adjustment to their doses of the component drugs, and have to take them separately, not as a single pill

Same side effects as

Edurant

  • Depression, mood changes
  • Nausea
  • Rash
  • Edurant has not been studied during pregnancy; tell your medical provider if you become pregnant while taking this drug

Viread

  • Gassiness; abdominal discomfort; nausea; diarrhea
  • Kidney impairment
  • Viread is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B

Emtriva

  • Skin discoloration (particularly in dark-skinned people)
  • Emtriva is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.